It goes by many names, including pot, grass, cannabis, weed, hemp, hash, . Older patients may have more problems with side effects and are. I was against it at first, but medical cannabis helped me through the side effects of chemotherapy and surgery when I had ovarian cancer. Cancer patients look to cannabis with two different —but not necessarily mutually exclusive— objectives: to alleviate the side effects of the cancer therapy and to.
for treatment and side cbd cancer effects thc
Likewise, no negative effects have been detected associated with the combination of drugs in other tests performed to analyse the analgesic effect of cannabinoid drugs in cases of neuropathic pain caused by the chemotherapy itself. Finally, and no less importantly, it is important to remember that one of the very few authorised medical uses of cannabinoid drugs is for the treatment of nausea and vomiting caused by chemotherapy.
In principle, at least, this suggests that the combination of the two therapeutic strategies should not cause any problem. While it is true that the accumulated preclinical and clinical evidence to date suggests that cannabis may be used safely in combination with chemotherapy and radiotherapy, there are a number of issues that still need to be examined in greater detail. One of them is the possible interference of cannabinoids —especially CBD— with the cytochrome p CYP detoxification system.
This system is responsible for metabolising many different compounds including many of the drugs we habitually take , oxidising them and thus transforming them into metabolites which are non-toxic for the body. It has been described that both THC and, in particular, CBD are capable of inhibiting certain CYP isoforms 7 , which might increase the half-life of the treatments processed by these enzymes, as a result of the non-metabolisation of the drugs.
Other compounds used by these patients, such as tamoxifen, are administered in the form of prodrugs, which only activate when processed by CYP. Thus the combination of these prodrugs with cannabinoids could, in principle, reduce the bioavailability of the corresponding active forms.
Finally, many of the drugs used by cancer patients antitumour drugs, anti-depressants, stomach protectors, analgesics, etc. However, none of these potential interactions appears significant enough to advise against the combined use of cannabis and other therapies.
Secondly, the as-yet scanty clinical experience suggests that such interactions can easily be managed by making small alterations to the dosage. For example, a potentially negative interaction has been described between CBD and clobazam Onfi , a benzodiazepine that is used as a coadjuvant in forms of epilepsy that do not respond to conventional treatments. The combined use of the two drugs was associated with greater levels of clobazam in plasma and an increase in its side effects following a typical pattern of excess dose.
These were easily reduced by lowering the dose of this compound 8. It is therefore important that patients who use cannabis for medicinal purposes report to their doctor to enable them to take these possible interactions into account and if necessary, adjust the dose of any treatment they are receiving.
Another issue that requires further analysis is the possible interference between cannabinoid treatments containing CBD and antioxidant supplements. This cannabinoid produces antitumour responses in different cell and animal models of cancer. Although the molecular mechanisms by which this effect occurs are very varied, one of the ones that appears to have greatest weight is the generation of reactive oxygen species 2 , precisely the type of compounds on which antioxidants exercise an effect.
One might therefore consider whether the antioxidant supplements could interfere with the potential anti-tumour action of CBD. Indeed, the use of antioxidants during antitumour therapy is still controversial among oncologists. On the one hand, the toxic effects on non-tumour cells of oxidative stress generated by the tumours themselves or by the therapy could be countered with antioxidant supplements.
However, these supplements might block the harmful effects of the oxidative stress on the tumour cells. For the time being, the consensus appears to be that there is still not enough scientific evidence to support the use of antioxidants in cancer patients during anti-tumour treatments 9. Finally, another issue that requires additional study is the use of cannabis during treatment with immunotherapy.
This is a type of therapeutic strategy that is increasingly being used in the area of oncology. Its ultimate aim is to stimulate the patient's immune response so that it destroys the tumour cells.
It has been widely demonstrated that different elements of the immune system B and T lymphocytes, macrophages, monocytes, etc. Results from some preclinical and clinical studies indicate that cannabinoids exercise immunosuppressant effects 10 , which could pose a potential problem when cannabis treatments are combined with immunotherapy.
However, there is no evidence whatsoever that the use even chronic of cannabis is associated with the appearance or aggravation of infectious diseases or tumours, even in immunocompromised individuals, such as for example HIV patients In any case, more research, both preclinical and clinical, is urgently needed to resolve all these queries and in order to be able to offer rigorous information to both patients and the health professionals who accompany them in their treatments.
Some of these may have medicinal value. These substances are known as cannabinoids. There are some drugs available that are derived from cannabis, for example Sativex, used for multiple sclerosis and Nabilone, used sometimes for sickness caused by chemotherapy. These go through the same processes as any other medicine to be licensed in the UK as a prescribable drug. There has been a lot of interest in cannabinoids.
Deltatetrahydrocannabidiol and cannabidiol have been studied to see if they could have any role in the treatment of cancer. Most of the scientific research has been done in a laboratory. Scientists have found that different cannabinoids can:. Some studies have looked at whether using cannabis may increase the risk of developing cancer. These have produced different results.
Some research has shown that using cannabis may protect against cancer. But other studies have shown an increased risk of cancer. It is still unclear whether using cannabis has any anti-cancer effects. But there is some evidence that the chemicals in cannabis might help with symptoms such as nausea and pain.
But these studies have had mixed results when used in clinical trials. Because of the mixed results, the general feeling of experts is that there needs to be more research into the chemicals found in cannabis and their possible benefit.
Cannabis, particularly cannabis oil, is a popular topic. Cannabis oil is only one of a number of treatments people might come across. It can be sold in the UK as long as it is sold as a food supplement and the sellers are not making any claim about its medicinal properties.
There are a number of examples where people say that using CBD oil has had a dramatic effect on their health. But these are individual stories and not based on clinical research trials. If you are thinking of using CBD oil, we suggest you talk to your healthcare team. If you are looking for information online you want to be sure that it is accurate and up to date. You can read more about finding quality information on our website.
Back to Complementary therapies explained You might be thinking about what you can do to look after yourself. Some people find complementary therapies lift their spirits and help them relax and cope with stress.
Mom was inoperable and we decided on no treatment, only palliative care. This is going over a year after diagnosis, but found out with research that she has had this awful tumor for about four years not, obviously getting worse. The worst part was those stent exchanges! Anyway, long story short, last recommendation was hospice.
Now since in obvious circumstances there is nothing to lose, I will check into cannabis for pain management. This is something so difficult to even convince her to use.
Once she tries it, I will share. Seriously, if someone is recommended at hospice what can one lose? This has been an endless challenge, and more power to everyone who is fighting this illness. I really have to thank everyone, patient and caretaker who tries hard to help. Curious to know if the continued used of Cannabis is still proving to work for your Mother in Law…. After 6 months of it and just getting a pet scan, her condition has improved dramatically. They gave her 8 months to live with chemo.
Needless to say we were surprised. Was it the cannabis? Was it the chemo? He was hoping to just stop it from growing and buying her some time. Oh, and to add to it, she had a cat scan about 3 months ago, and it showed the tumors were all the same size as when treatment started. I was diagnosed and an through 3 chemo treatments so far.
My mother in law is taking cannibis oil with chemo. She just started and we put it in capsules with coconut oil for her to take. Once the buzz feeling goes away, she may see about taking another capsule during the day.
She needs to work up to 1g per day. Hi, I use canabbis oil. With it I have not used painkillers Tylenol nor oxycodone , nausea pills ondasetron , anxiolytics rivotril or docusate to go to the bathroom — I feel great. If you can use it. My doctor also said it was ok. Viewing 15 posts - 1 through 15 of 17 total.
CANNABIS OIL & CHEMO?
The National Cancer Institute states that cannabinoids such as CBD and THC are useful in treating the side effects of cancer, and can ease the. Many people diagnosed with cancer feel that CBD is better at controlling People use marijuana to ease the side effects of treatment and pain. So, if it did have THC in it, would the doctors refuse chemo? and if it was . The side effects can be managed these days to a high degree and.