Pure and Organic CBD & and Hemp Products

Effective medicine provided by mother nature

  • Powerful relaxant

  • Strong painkiller

  • Stress reduction
  • Energy booster

Why CBD?

More and more renowned scientists worldwide publish their researches on the favorable impact of CBD on the human body. Not only does this natural compound deal with physical symptoms, but also it helps with emotional disorders. Distinctly positive results with no side effects make CBD products nothing but a phenomenal success.

This organic product helps cope with:

  • Tight muscles
  • Joint pain
  • Stress and anxiety
  • Depression
  • Sleep disorder

Range of Products

We have created a range of products so you can pick the most convenient ones depending on your needs and likes.

CBD Capsules Morning/Day/Night:

CBD Capsules

These capsules increase the energy level as you fight stress and sleep disorder. Only 1-2 capsules every day with your supplements will help you address fatigue and anxiety and improve your overall state of health.

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CBD Tincture

CBD Tincture

No more muscle tension, joints inflammation and backache with this easy-to-use dropper. Combined with coconut oil, CBD Tincture purifies the body and relieves pain. And the bottle is of such a convenient size that you can always take it with you.

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Pure CBD Freeze

Pure CBD Freeze

Even the most excruciating pain can be dealt with the help of this effective natural CBD-freeze. Once applied on the skin, this product will localize the pain without ever getting into the bloodstream.

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Pure CBD Lotion

Pure CBD Lotion

This lotion offers you multiple advantages. First, it moisturizes the skin to make elastic. And second, it takes care of the inflammation and pain. Coconut oil and Shia butter is extremely beneficial for the health and beauty of your skin.

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Biosynthetic Pathways Leading to the Different Classes of Terpenes

Replace Can Antidepressants? CBD



  • Replace Can Antidepressants? CBD
  • Cannabinoids, Neurogenesis and Antidepressant Drugs: Is there a Link?
  • Introduction
  • Instead of adding CBD to an antidepressant regimen, it may be more ideal for you to be able to stop using. Sadie takes cannabidiol (CBD) to calm her korean-war.infosy of Cory American Shaman does not believe in hard sell tactics. Gleichenhaus. In his letter he explains how cannabis can not only provide the and pharmaceutical medications like benzodiazepines, antidepressants, beta.

    Replace Can Antidepressants? CBD

    If you are planning to replace your medications with CBD, it is really important to consult with your doctor first and he should monitor your whole process. Your doctor will lower the dose of the antidepressants that you are taking in the first several months. During this period, you will continue to take CBD every day.

    As time passes, your doctor will start to increase the dosage of CBD oil. Finally, after some time you will completely stop using antidepressants. Quitting your antidepressant medication all of a sudden may cause a range of withdrawal symptoms. Some of the side effects include:. One of the most frequent asked questions is how much CBD oil should be taken to treat depression.

    Well, there is no standard answer to this, because it varies. The main reason is that CBD is acting differently in each individual. That is why you should be fully informed on how much CBD oil you should consume before starting using it. Finding the right amount of CBD oil will be personal to you. Also, your weight and your height play a great role too. If you have some type of medical condition, it is best to consult your doctor before taking CBD oil. It is ideal to start with a lower dose first and building up.

    There are no official guidelines for the amount and time needed for the CBD oil to show its full effect, so time and patience are the keys to finding the dose which is most effective. On your first day of use, start with only one drop. Starting with this low dose gives your body time to adapt to the CBD. After two to three days, increase your dose to 2 drops per day for the next few weeks.

    During this time, you should see if you notice any visible reduction in your depression symptoms. Be aware that it takes time for CBD to affect you, so it might take a while before you can notice some changes.

    You can separate your dose into a few smaller doses throughout the day, in order to enhance the absorption and efficacy of the oil. According to the researches done from the users of CBD oil, doses from 40 mg to mg are the most effective. But, still this is a wide range of number, and it varies from individual to individual.

    CBD oil is legal and available for sale. CBD oil can hinder hepatic drug metabolism and the activity of some enzymes in the liver. Some of the users have also reported a dry mouth after using the CBD oil. Your first weeks without your medicines might be rough for you. You might get anxiety attacks, have sleep disorders. Depression can also be linked to suicidal thoughts. Suicide has been in the news frequently recently—from the sudden, shocking losses of Kate Spade and Anthony Bourdain, to a recent Centers for Disease Control and Prevention study showing an increase of 25 percent in suicides between and , with Washington State specifically increasing at a rate of During roughly that same time period from to , antidepressant use went up by 65 percent.

    In , nearly one in eight Americans aged 12 or older had recently used an antidepressant. But as medical and recreational cannabis programs have led to expanded safe access and better education in self-medication, people who have previously used antidepressants are trying out cannabis treatments.

    One Canadian study in showed 63 percent of patients reported using medical marijuana as a substitute for prescription drugs, such as opioids, sedatives, and antidepressants. Trying to find a particular cannabis strain to deal with depression can be overwhelming.

    Stress inhibits the proliferation of granule cell precursors in the developing dentate gyrus. Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. The neurogenesis hypothesis of affective and anxiety disorders: Mirescu C, Gould E. Stress and adult neurogenesis. Adult hippocampal neurogenesis buffers stress responses and depressive behaviour.

    Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. Lithium selectively increases neuronal differentiation of hippocampal neural progenitor cells both in vitro and in vivo. Biogenic amines and their impact in psychiatry. Monoamine precursors in the treatment of depression. Receptor sensitivity and the mechanism of action of antidepressant treatment. Implications for the etiology and therapy of depression. Monoamines, depression and antidepressant drugs.

    Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan. Briley M, Moret C. Maturational sequence of newly generated neurons in the dentate gyrus of the young adult rhesus monkey. Cell proliferation in adult hippocampus is decreased by inescapable stress: High-speed imaging reveals neurophysiological links to behavior in an animal model of depression.

    Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal. Paradoxical influence of hippocampal neurogenesis on working memory. Hippocampal cell proliferation regulation by repeated stress and antidepressants.

    Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice. Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primates. Serotonin stimulates the production of new hippocampal granule neurons via the 5-HT1A receptor in the adult rat.

    Ventral hippocampal molecular pathways and impaired neurogenesis associated with 5-HT 1A and 5-HT 1B receptors disruption in mice. Noradrenaline increases neural precursor cells derived from adult rat dentate gyrus through beta2 receptor. Norepinephrinedirectlyactivatesa- dulthippocampalprecursors via beta3-adrenergic receptors. Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus.

    VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants. Regulation of adult neurogenesis by antidepressant treatment.

    Antidepressants stimulate hippocampal neurogenesis by inhibiting p21 expression in the subgranular zone of the hipppocampus. Gaoni Y, Mechoulam R. The isolation and structure of deltatetrahydrocannabinol and other neutral cannabinoids from hashish.

    Mechoulam R, Braun P, aoni Y. Syntheses of 1 -tetrahydrocannabinol and related cannabinoids. International Union of Basic and Clinical Pharmacology. Cannabinoid receptors and their ligands: Stereochemical requirements for cannabinoid activity. Pharmacology and stereoselectivity of structurally novel cannabinoids in mice.

    Involvement of Gi in the inhibition of adenylatecyclase by cannabimimetic drugs. Glass M, Northup JK. International Union of Pharmacology. Classification of cannabinoid receptors. An overview on the biochemistry of the cannabinoid system. Postsynaptic localization of CB2 cannabinoid receptors in the rat hippocampus. Moldrich G, Wenger T.

    Localization of the CB1 cannabinoid receptor in the rat brain. Immunocytochemical distribution of the cannabinoid CB1 receptor in the primate neocortex: Anxiolytic effects in mice of a dual blocker of fatty acid amide hydrolase and transient receptor potential vanilloid type-1 channels. Neuropsychobiological evidence for the functional presence and expression of cannabinoid CB2 receptors in the brain. Effects of cannabidiol in animal models predictive of antipsychotic activity.

    Psychopharmacology Berl ; 2: Antianxiety effect of cannabidiol in the elevated plus-maze. Psychopharmacology Berl ; 4: Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test. Anxiolytic-like effect of cannabinoids injected into the rat dorsolateral periaquidutal gray. Szabo B, Schlicker E. Effects of cannabinoids on neurotransmission. Diana MA, Marty A.

    Endocannabinoid-mediated short-term synaptic plasticity: The cannabinoid CB1 receptor mediates retrograde signals for depolarization-induced suppression of inhibition in cerebellar Purkinje cells.

    Presynaptic cannabinoid sensitivity is a major determinant of depolarization-induced retrograde suppression at hippocampal synapses. Depolarization-induced suppression of inhibition mediated by endocannabinoids at synapses from fast-spiking interneurons to medium spiny neurons in the striatum.

    Regulatory role of cannabinoid receptor 1 in stress-induced excitotoxicity and neuroinflammation. CB1 cannabinoid receptors and on-demand defense against excitotoxicity. Shen M, Thayer SA. Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity. The emerging functions of endocannabinoid signaling during CNS development.

    The endocannabinoid system drives neural progenitor proliferation. Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation.

    Expression and function of cannabinoid receptors CB1 and CB2 and their cognate cannabinoid ligands in murine embryonic stem cells. The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis.

    A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner. Cannabinoid agonist WIN, partially restores neurogenesis in the aged rat brain. Endocannabinoids modulate stress-induced suppression of hippocampal cell proliferation and activation of defensive behaviours.

    Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis. The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: Acute cannabinoids impair working memory through astroglial CB1 receptor mod ulation of hippocampal LTD.

    Sub-chronic administration of rimonabant causes loss of antidepressive activity and decreases doublecortinimmunoreactivity in the mouse hippocampus. Defective adult neurogenesis in CB1 cannabinoid receptor knockout mice. Chen C, Bazan NG. Endogenous PGE2 regulates membrane excitability and synaptic transmission in hippocampal CA1 pyramidal neurons. Electroconvulsive shock treatment differentially modulates cortical and subcortical endocannabinoid activity.

    Involvement of the endocannabinoid system in the ability of long-term tricyclic antidepressant treatment to suppress stress-induced activation of the hypothalamic-pituitary-adrenal axis. Regional alterations in the endocannabinoid system in an animal model of depression: Downregulation of endocannabinoid signaling in the hippocampus following chronic unpredictable stress. Differential effects of the antidepressants tranylcypromine and fluoxetine on limbic cannabinoid receptor binding and endocannabinoid contents.

    Long-term fluoxetine treatment modulates cannabinoid type 1 receptor-mediated inhibition of adenylyl cyclase in the rat prefrontal cortex through 5-hydroxytryptamine 1A receptor-dependent mechanisms. Effects of chronic treatment with citalopram on cannabinoid and opioid receptor-mediated G-protein coupling in discrete rat brain regions. Psychopharmacology Berl ; 1: CB-1 receptors modulate the effect of the selective serotonin reuptake inhibitor citalopram on extracellular serotonin levels in the rat prefrontal cortex.

    Cannabinoids, Neurogenesis and Antidepressant Drugs: Is there a Link?

    When I first started using CBD in late , I was astounded by how well it worked for me. I used sublingual sprays & tinctures, which have the highest. I am curious to know if anyone has had success with CBD or Hemp oil better by then I most likely will need to go back on an anti-depressant. To prove its efficacy, we analyzed a series of CBD studies over the last 10 years and see a very clear connection between CBD and its use as an antidepressant. You can also ingest more CBD in the form of tinctures or pills to combat these.




    When I first started using CBD in late , I was astounded by how well it worked for me. I used sublingual sprays & tinctures, which have the highest.


    I am curious to know if anyone has had success with CBD or Hemp oil better by then I most likely will need to go back on an anti-depressant.


    To prove its efficacy, we analyzed a series of CBD studies over the last 10 years and see a very clear connection between CBD and its use as an antidepressant. You can also ingest more CBD in the form of tinctures or pills to combat these.


    CBD can treat schizophrenia, post traumatic stress, epileptic disorders, depression, anxiety, cancer, osteoporosis, nausea, lupus, OCD.


    Mixing cannabis with antidepressants can result in a major central nervous Could Medical Marijuana Replace Some Prescription Drugs?.

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