Learn about CBD, what it is, how it works, side effects, and how it could help you with depression. including its effects on anxiety and depression, as well as on social anxiety There have been extensive reviews on the toxic potentials of CBD and CBD oil helps to significantly improve depressive symptoms and the . Feb 24, had success with CBD or Hemp oil helping with depression/anxiety? but would like thoughts/opinions from anyone who has actually tried it. Jul 27, Stressed, anxious, and depressed woman holds her hands across her chest. People interested in managing their anxiety with CBD oil should look PhD, MSN, RN, IBCLC, AHN-BC, CHT Answers represent the opinions of.
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Yet excessive or persistent fear may be maladaptive, leading to disability. Symptoms arising from excessive fear and anxiety occur in a number of neuropsychiatric disorders, including generalized anxiety disorder GAD , panic disorder PD , post-traumatic stress disorder PTSD , social anxiety disorder SAD , and obsessive—compulsive disorder OCD.
Notably, PTSD and OCD are no longer classified as anxiety disorders in the recent revision of the Diagnostic and Statistical Manual of Mental Disorders-5; however, excessive anxiety is central to the symptomatology of both disorders.
These anxiety-related disorders are associated with a diminished sense of well-being, elevated rates of unemployment and relationship breakdown, and elevated suicide risk [ 1 — 3 ]. Currently available pharmacological treatments include serotonin reuptake inhibitors, serotonin—norepinephrine reuptake inhibitors, benzodiazepines, monoamine oxidase inhibitors, tricyclic antidepressant drugs, and partial 5-hydroxytryptamine 5-HT 1A receptor agonists.
Anticonvulsants and atypical antipsychotics are also used to treat PTSD. These medications are associated with limited response rates and residual symptoms, particularly in PTSD, and adverse effects may also limit tolerability and adherence [ 7 — 10 ]. The substantial burden of anxiety-related disorders and the limitations of current treatments place a high priority on developing novel pharmaceutical treatments. CBD has broad therapeutic properties across a range of neuropsychiatric disorders, stemming from diverse central nervous system actions [ 11 , 12 ].
In recent years, CBD has attracted increasing interest as a potential anxiolytic treatment [ 13 — 15 ]. The purpose of this review is to assess evidence from current preclinical, clinical, and epidemiological studies pertaining to the potential risks and benefits of CBD as a treatment for anxiety disorders.
In total, 49 primary preclinical, clinical, or epidemiological studies were included. Neuroimaging studies that documented results from anxiety-related tasks, or resting neural activity, were included. THC ratio , were included. Cannabis sativa , a species of the Cannabis genus of flowering plants, is one of the most frequently used illicit recreational substances in Western culture.
The 2 major phyto- cannabinoid constituents with central nervous system activity are THC, responsible for the euphoric and mind-altering effects, and CBD, which lacks these psychoactive effects.
Preclinical and clinical studies show CBD possesses a wide range of therapeutic properties, including antipsychotic, analgesic, neuroprotective, anticonvulsant, antiemetic, antioxidant, anti-inflammatory, antiarthritic, and antineoplastic properties see [ 11 , 12 , 16 — 19 ] for reviews. Pharmacology relevant to these actions is detailed below.
The primary mechanism by which eCBs regulate synaptic function is retrograde signaling, wherein eCBs produced by depolarization of the postsynaptic neuron activate presynaptic CB 1 Rs, leading to inhibition of neurotransmitter release [ 23 ]. Interactions with the TRPV1 receptor, in particular, appear to be critical in regulating the extent to which eCB release leads to inhibition or facilitation of presynaptic neurotransmitter release [ 25 ].
TRPV1 receptors are also expressed in the brain, including the amygdala, periaqueductal grey, hippocampus, and other areas [ 26 , 27 ]. The eCB system regulates diverse physiological functions, including caloric energy balance and immune function [ 28 ].
The eCB system is also integral to regulation of emotional behavior, being essential to forms of synaptic plasticity that determine learning and response to emotionally salient, particularly highly aversive events [ 29 , 30 ]. Activation of CB 1 Rs produces anxiolytic effects in various models of unconditioned fear, relevant to multiple anxiety disorder symptom domains reviewed in [ 30 — 33 ]. Regarding conditioned fear, the effect of CB 1 R activation is complex: CB 1 R activation may enhance or reduce fear expression, depending on brain locus and the eCB ligand [ 34 ]; however, CB 1 R activation potently enhances fear extinction [ 35 ], and can prevent fear reconsolidation.
Genetic manipulations that impede CB 1 R activation are anxiogenic [ 35 ], and individuals with eCB system gene polymorphisms that reduce eCB tone—for example, FAAH gene polymorphisms—exhibit physiological, psychological, and neuroimaging features consistent with impaired fear regulation [ 36 ].
Reduction of AEA—CB 1 R signaling in the amygdala mediates the anxiogenic effects of corticotropin-releasing hormone [ 37 ], and CB 1 R activation is essential to negative feedback of the neuroendocrine stress response, and protects against the adverse effects of chronic stress [ 38 , 39 ]. Accordingly, CB 1 R activation has been suggested as a target for anxiolytic drug development [ 15 , 43 , 44 ].
In addition to dose-dependent activation of TRPV1 channels, the anxiogenic versus anxiolytic balance of CB 1 R agonists also depends on dynamic factors, including environmental stressors [ 33 , 49 ]. In preclinical studies, 5-HT 1A R agonists are anxiolytic in animal models of general anxiety [ 51 ], prevent the adverse effects of stress [ 52 ], and enhance fear extinction [ 53 ]. They are expressed on serotonergic neurons in the raphe, where they exert autoinhibitory function, and various other brain areas involved in fear and anxiety [ 54 , 55 ].
Mechanisms underlying the anxiolytic effects of 5-HT 1A R activation are complex, varying between both brain region, and pre- versus postsynaptic locus, and are not fully established [ 56 ]. Initial studies of CBD in these models showed conflicting results: When tested over a wide range of doses in further studies, the anxiolytic effects of CBD presented a bell-shaped dose—response curve, with anxiolytic effects observed at moderate but not higher doses [ 61 , 90 ].
All further studies of acute systemic CBD without prior stress showed anxiolytic effects or no effect [ 62 , 65 ], the latter study involving intracerebroventricular rather than the intraperitoneal route. No anxiogenic effects of acute systemic CBD dosing in models of general anxiety have yet been reported.
As yet, few studies have examined chronic dosing effects of CBD in models of generalized anxiety. Anxiolytic effects in models used: Anxiolytic effects of CBD in models of generalized anxiety have been linked to specific receptor mechanisms and brain regions. The midbrain dorsal periaqueductal gray DPAG is integral to anxiety, orchestrating autonomic and behavioral responses to threat [ 91 ], and DPAG stimulation in humans produces feelings of intense distress and dread [ 92 ].
The bed nucleus of the stria terminalis BNST serves as a principal output structure of the amygdaloid complex to coordinate sustained fear responses, relevant to anxiety [ 93 ]. In the prelimbic cortex, which drives expression of fear responses via connections with the amygdala [ 94 ], CBD had more complex effects: As noted, CBD has been found to have a bell-shaped response curve, with higher doses being ineffective. Stress is an important contributor to anxiety disorders, and traumatic stress exposure is essential to the development of PTSD.
In a chronic study, systemic CBD prevented increased anxiety produced by chronic unpredictable stress, in addition to increasing hippocampal AEA; these anxiolytic effects depended upon CB 1 R activation and hippocampal neurogenesis, as demonstrated by genetic ablation techniques [ 81 ]. Finally, CBD, partially via CB 1 Rs, decreased defensive immobility and explosive escape caused by bicuculline-induced neuronal activation in the superior colliculus [ 89 ].
Several studies assessed CBD using contextual fear conditioning. Briefly, this paradigm involves pairing a neutral context, the conditioned stimulus CS , with an aversive unconditioned stimulus US , a mild foot shock. After repeated pairings, the subject learns that the CS predicts the US, and subsequent CS presentation elicits freezing and other physiological responses. By contrast, CBD microinjection in the infralimbic cortex enhanced conditioned freezing [ 70 ].
Finally, El Batsh et al. In this study, CBD was administered prior to conditioning rather than prior to re-exposure as in acute studies, thus further directly comparable studies are required. CBD has also been shown to enhance extinction of contextually conditioned fear responses. Extinction training involves repeated CS exposure in the absence of the US, leading to the formation of a new memory that inhibits fear responses and a decline in freezing over subsequent training sessions.
Further studies showed CB 1 Rs in the infralimbic cortex may be involved in this effect [ 82 ]. CBD also blocked reconsolidation of aversive memories in rat [ 76 ]. Briefly, fear memories, when reactivated by re-exposure retrieval , enter into a labile state in which the memory trace may either be reconsolidated or extinguished [ 97 ], and this process may be pharmacologically modulated to achieve reconsolidation blockade or extinction.
Overall, existing preclinical evidence strongly supports the potential of CBD as a treatment for anxiety disorders. Activation of 5-HT 1A Rs appears to mediate anxiolytic and panicolytic effects, in addition to reducing conditioned fear expression, although CB 1 R activation may play a limited role.
While CBD predominantly has acute anxiolytic effects, some species discrepancies are apparent. In addition, effects may be contingent on prior stress and vary according to brain region. Further receptor-specific studies may elucidate the receptor specific basis of this distinct dose response profile.
Further studies are also required to establish the efficacy of CBD when administered in chronic dosing, as relatively few relevant studies exist, with mixed results, including both anxiolytic and anxiogenic outcomes.
In particular, results show potential for the treatment of multiple PTSD symptom domains, including reducing arousal and avoidance, preventing the long-term adverse effects of stress, as well as enhancing the extinction and blocking the reconsolidation of persistent fear memories. The anxiolytic effects of CBD in humans were first demonstrated in the context of reversing the anxiogenic effects of THC. CBD reduced THC-induced anxiety when administered simultaneously with this agent, but had no effect on baseline anxiety when administered alone [ 99 , ].
Further studies using higher doses supported a lack of anxiolytic effects at baseline [ , ]. By contrast, CBD potently reduces experimentally induced anxiety or fear. CBD reduced anxiety associated with a simulated public speaking test in healthy subjects, and in subjects with SAD, showing a comparable efficacy to ipsapirone a 5-HT 1A R agonist or diazepam [ 98 , ].
CBD also reduced the presumed anticipatory anxiety associated with undergoing a single-photon emission computed tomography SPECT imaging procedure, in both healthy and SAD subjects [ , ]. Finally, CBD enhanced extinction of fear memories in healthy volunteers: These rCBF changes were not correlated with anxiolytic effects [ ].
In a series of placebo-controlled studies involving 15 healthy volunteers, Fusar-Poli et al. Response activation is diminished in PTSD and other anxiety disorders, and increased activation predicts response to treatment [ ]. CBD produced no changes in predicted areas relative to placebo but reduced activation in the left insula, superior temporal gyrus, and transverse temporal gyrus. The fearful faces task activates the amygdala, and other medial temporal areas involved in emotion processing, and heightened amygdala response activation has been reported in anxiety disorders, including GAD and PTSD [ , ].
CBD attenuated blood-oxygen-level dependent activation in the left amygdala, and the anterior and posterior cingulate cortex in response to intensely fearful faces, and also reduced amplitude in skin conductance fluctuation, which was highly correlated with amygdala activation [ ].
Dynamic causal modeling analysis in this data set further showed CBD reduced forward functional connectivity between the amygdala and anterior cingulate cortex [ ]. Epidemiological studies of various neuropsychiatric disorders indicate that a higher CBD content in chronically consumed cannabis may protect against adverse effects of THC, including psychotic symptoms, drug cravings, memory loss, and hippocampal gray matter loss [ — ] reviewed in [ ].
As THC acutely induces anxiety, this pattern may also be evident for chronic anxiety symptoms. Two studies were identified, including an uncontrolled retrospective study in civilian patients with PTSD patients [ ], and a case study in a patient with severe sexual abuse-related PTSD [ ], which showed that chronic cannabis use significantly reduces PTSD symptoms; however, these studies did not include data on the THC: Thus, overall, no outcome data are currently available regarding the chronic effects of CBD in the treatment of anxiety symptoms, nor do any data exist regarding the potential protective effects of CBD on anxiety potentially induced by chronic THC use.
Evidence from human studies strongly supports the potential for CBD as a treatment for anxiety disorders: Limited results in healthy subjects also support the efficacy of CBD in acutely enhancing fear extinction, suggesting potential for the treatment of PTSD, or for enhancing cognitive behavioral therapy.
Further studies are also required to establish whether chronic, in addition to acute CBD dosing is anxiolytic in human. Human experimental findings support preclinical findings, and also suggest a lack of anxiogenic effects, minimal sedative effects, and an excellent safety profile. Overall, this review emphasizes the potential value and need for further study of CBD in the treatment of anxiety disorders.
Disclosure forms provided by the authors are available with the online version of this article. National Center for Biotechnology Information , U. Journal List Neurotherapeutics v. Published online Sep 4. Blessing , 1 Maria M. Steenkamp , 1 Jorge Manzanares , 1, 2 and Charles R. Author information Copyright and License information Disclaimer. This article has been cited by other articles in PMC. Abstract Cannabidiol CBD , a Cannabis sativa constituent, is a pharmacologically broad-spectrum drug that in recent years has drawn increasing interest as a treatment for a range of neuropsychiatric disorders.
Electronic supplementary material The online version of this article doi: Cannabidiol, Endocannabinoids, Anxiety, Generalized anxiety disorder, Post-traumatic stress disorder.
Introduction Fear and anxiety are adaptive responses essential to coping with threats to survival. CBD Pharmacology Relevant to Anxiety General Pharmacology and Therapeutic Profile Cannabis sativa , a species of the Cannabis genus of flowering plants, is one of the most frequently used illicit recreational substances in Western culture.
Table 1 Preclinical studies. Open in a separate window. Effective doses are in bold Receptor specific agents: Stress-induced Anxiety Models Stress is an important contributor to anxiety disorders, and traumatic stress exposure is essential to the development of PTSD. Summary and Clinical Relevance Overall, existing preclinical evidence strongly supports the potential of CBD as a treatment for anxiety disorders. Table 2 Human psychological studies. Table 3 Neuroimaging studies. Evidence from Epidemiological and Chronic Studies Epidemiological studies of various neuropsychiatric disorders indicate that a higher CBD content in chronically consumed cannabis may protect against adverse effects of THC, including psychotic symptoms, drug cravings, memory loss, and hippocampal gray matter loss [ — ] reviewed in [ ].
Summary and Clinical Relevance Evidence from human studies strongly supports the potential for CBD as a treatment for anxiety disorders: Electronic supplementary material Below is the link to the electronic supplementary material.
Required Author Forms Disclosure forms provided by the authors are available with the online version of this article. Anxiety disorders in primary care: Suicide risk in patients with anxiety disorders: Quality of life in the anxiety disorders: Twelve-month use of mental health services in the United States: Cost of disorders of the brain in Europe An effect-size analysis of the relative efficacy and tolerability of serotonin selective reuptake inhibitors for panic disorder. Remission rates in patients with anxiety disorders treated with paroxetine.
Adjunctive risperidone treatment for antidepressant-resistant symptoms of chronic military service-related PTSD: Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug.
Antidepressant-like and anxiolytic-like effects of cannabidiol: And so, I was surprised at the difference CBD made to my health. My neck pain around my 3 herniated discs eased. My lower back pain was relieved which has given me so much pain since I was You have many options when it comes to purchasing CBD oil online, and so it can become very time consuming choosing the CBD oil, capsules, or other product for your needs.
Here are my reviews of the best ones. All of their products undergo rigorous testing with the use of advanced HPLC equipment. Additionally, they also have their products tested in a certified GMP facility in Florida. Your discount will be applied when you checkout. Discount will be shown at checkout. TeraHemp provides lab tested, top rated CBD products that are are made from industrial grade hemp oil.
This type of cannabidiol has been touted anecdotally by cancer patients — and it has been shown to be effective at fighting cancer in human cells in research labs. This is a top-rated cannabidiol brand if you like your CBD made from high-quality hemp and you want free shipping within the USA. Just use this code when you checkout. Bota Hemp begins its great reputation by being a part of the National Hemp Association. While they may not offer as many different products as other companies, they make up for this in the quality of their products.
Their full spectrum CBD tincture comes in mg, mg, and mg. It only has trace amounts of THC coming in at 0. This is a top CBD oil to use if you prefer to go the organic route with everything and need a way to de-stress and relieve symptoms associated with an anxiety disorder. Bota Hemp also offers the same product in capsule form as well.
When it comes to the extraction process, it uses pure CO2 to make sure that the minimal amount of impurities are transferred as a result. Hemp Bombs not only sticks to incredibly stringent European regulations around their processing and manufacturing, but they also make sure that every single one of their products goes through rigorous third-party testing.
They display these results for both existing and potential customers on their website. When it comes to Hemp Bombs products, you can get them in five different concentrations. These are mg, mg, mg, mg, and mg. Because the strength of their oil is so concentrated, you only need to take between one and two drops under your tongue to experience the full effects. We recommend holding it there for a couple of minutes so that it has time to absorb properly.
Because Hemp Bombs is keen to maintain its reputation in the CBD oil industry, it is currently expanding its product line. Their newest addition is CBD oil gummies that come in four different sizes and strengths. You can get it in two different sizes, and you can easily just rub it on the affected area before you start to feel the effects immediately. Hemp Bombs also has a natural hemp syrup that includes a number of highly concentrated botanicals to help you relax.
It can also contribute to an increase in mood, as well. Whether you add it to your favorite drink or take it as it is, you know that you can just sit back and enjoy the positive effects.
There is absolutely no question around that Hemp Bomb products are of the highest quality. Not only do they have a fantastic customer service team, but they also offer ongoing benefits for regular customers.
For example, if you subscribe to your newsletter, you get regular discounts on their products. As well as being some of the purest e-liquid that you can buy, it also comes in some fantastic flavors. Definitely worth giving your money to. While round numbers are great for a lot of people, sometimes patients with medical conditions need something a little bit more specific to suit their needs better.
NuLeaf Naturals accommodates for this, supplying you with CBD oil in a number of less conventional concentration amounts: This range means that they can cater to a much higher level of customers, and each customer can be guaranteed to find a strength that works for their needs. NuLeaf Naturals even offers free shipping on all orders within the United States. CBD users who prefer products that are full spectrum Those who have unconventional concentration preferences Caters to eco-friendly shoppers Highlights: Tinctures Full Spectrum Largest variety of concentrations.
Elixinol has been in the CBD oil game since Their goal when they formed was not only to create one of the highest quality CBD hemp products in the industry but also to use this to help people who are dealing with everyday medical conditions. Elixinol cares a lot about the quality of their product. They test for heavy metals, pesticides, and mycotoxins in all their products.
They publish these batch tested results on their website for you to see. Elixinol works with a CO2 extraction process that allows the CBD oil to include all the essential compounds of the original plant. Almost thirty years of experience in this industry has led Elixinol to master the art of the oral applicator, that protects against UV, air pockets and prevents you from wasting any of your product.
I recommend this CBD oil as a great natural alternative to pain medication. A lot of the time, CBD oil products can be pretty expensive. Endoca offers you two options when it comes to CBD oil. Endoca also offers capsules, pills, skin cream suppositories, and CBD infused chewing gum. The rest of these products are also low cost as well. Endoca also offers a full refund on un-opened merchandise within two weeks of purchase. The CBDistillery was created by a group of Colorado natives who wanted the world to know about the benefits of CBD oil for everyday medical conditions.
In fact, they used the hashtag cbdmovement to gain traction and help people become more informed about the industry. The two largest sizes of the tincture full-spectrum CBD oil come in 30ml bottles, while the other sizes all come in 15ml bottles. Their largest size, the mg bottle, is very strong and has enough CBD oil for you to keep supplied for weeks on end, if not months.
For this reason, The CBDistillery is a great option for people who require high daily doses. Their lab tests are on display on each of their labels, so you know exactly what is in your purchase. The mg bottle contains 6. All oils contain a full-spectrum of phytocannabinoids. Their products are lab-tested and they provide fast shipping from the UK to anywhere in the world.
CBD is a naturally occurring oil. It is one of the largest cannabinoids found in marijuana and hemp. Our ones are known as endocannabinoids, and we even have a system called the endocannabinoid system, or ECS. The ECS encourages homeostasis in our bodies by being in charge of a broad range of functions.
These include appetite, mood, sleep, and motor skills. As we get older, our ECS as capable of producing fewer endocannabinoids. Disease of physical injury can also reduce the production of them, as well. Using CBD oil to replenish these lost endocannabinoids can help to restore overall balance in the body. First off, this product has gained momentum in the medical marijuana field because it possesses medicinal properties without any psychoactive effects that come with unprocessed marijuana.
Additionally, these products are beneficial for a wide range of medical conditions including muscle spasms, chronic pain and anxiety. The oil also helps relieve insomnia, convulsions, ulcers and neuropathic pain.
As you may have guessed, the question of legality around CBD oil in recent years has been quite a contentious issue. Because CBD oil does not have any psychoactive side effects and the hemp plant is not a controlled substance, products that are hemp-based are available to purchase, buy and possess in all 50 states in America.
However, when it comes to CBD oils, the law is slightly more complicated. According to a Farm Bill passed in , hemp should only be cultivated and grown for academic research. This technically means that any hemp-based product that is grown for anything other this purpose is illegal. However, this law is hardly ever enforced. To make it even more complicated, the laws surrounding this are somewhat unclear in specific states, too. Senator Mitch McConnell in Kentucky introduced legislation recently that legalized all hemp products on a federal level.
However, this decision is still pending. Because CBD oil is considered therapeutic, it is a low-risk alternative medicine for most users. However, it may bring on the following side effects:. The two have a chemical composition that is nearly similar, but the way they act is totally different. Both these compounds exist in a crystalline form that covers the mature cannabis flowers, and they form the highest concentration of active chemicals found in this plant.
THC forms the most psychoactive component in Cannabis plant. It binds to the cannabinoid 1 receptors, which are in the brain and the central nervous system. When THC is discussed by experts, this feeling is what makes it worrisome, making users get addicted to marijuana and the path to harder substance abuse. THC works by attaching to certain Cannabinoid receptors.
It activates these receptors and activates them, altering your behavior, hunger, fatigue, consciousness and mood perception. It simulates the effects of the natural neurotransmitter called anandamide that is known to impact eating and sleeping habits. This compound is considered to be the star of the cannabis show because it comes with many potential health benefits.
Health benefits of CBD include providing relief from convulsions, anxiety, inflammation, nausea and anxiety. It has also shown anti-cancer properties on breast cancer via inhibiting the growth of cancer cells. Apart from having nearly the same chemical composition, these two have totally different reactions when consumed.
Let us explore these differences. It is also the major cause of addiction and withdrawal symptoms. This is disappointing to many of those looking for recreational uses, but makes it ideal for use as medicine. This is the reason doctors are starting to prescribe CBD over THC; because they are looking for treatments that come with minimum side effects. This fact also makes CBD ideal for treating younger patients suffering from various ailments.
The use of CBD counteracts this effect and helps to prevent you from getting too high. Used by itself, CBD can potentially be used as an antipsychotic treatment for people suffering from schizophrenia.
The use of THC makes people feel paranoid and anxious. However, CBD is believed to have an opposite effect when it comes to treating anxiety.
Most people have warmed up to the idea of using marijuana because of its effect on sleep. The compound that brings this about is THC. On the other hand, CBD promotes wakefulness, making it ideal for boosting energy. The two components of cannabis have been well documented with the effects of each component clearly outlined. THC, on the other hand, gives you the head rush common with marijuana. CBD is considered technically legal in many places, and the world is opening up to its medicinal properties.
The health benefits of CBD oil are diverse. The world has seen a dramatic rise in the use of medicinal cannabis, with reports indicating that this oil can effectively control symptoms for a wide range of illnesses.
John not his real name had surgery on his L5 disk, but even with the conventional treatments he had to deal with lingering inflammation for months after the surgery. He decided to try CBD oils. He now takes 50 mg each day as compared to mg of ibuprofen that he had to take before. One of the largest and most nagging conditions is back pain. This can include all areas of the spine, such as the cervical neck spine, thoracic spine, and lumbar spine.
Most patients have enjoyed great relief thanks to CBD oil. CBD oil is beneficial because it comes in great flavors and an easy-to-control dosing system. This inflammation can lead to pain and if left unattended, can cause tissue damage. However, long-term use of these drugs has disastrous effects on the kidney, liver and the stomach. On the other hand, CBD oil has natural anti-inflammatory properties that relieve pain without any side-effects.
Studies show that between 10 and 50 percent of post-surgical patients experience acute pain which might turn chronic if not handled properly. Chronic pain can last more than six months. This is not fun at all. Many patients have discovered the benefits of CBD oil in treating post-surgical pain. CBD works by controlling the pain signals that are active in the spinal cord. One of the ways to relieve chronic pain is by exercising sore muscles. This only works when you can move the particular joint or part of the body.
A dosage of CBD oil relaxes the muscles, making it easy for you to move the joint without feeling pain. When you are sick, the best remedy is usually for you to get enough sleep. This sleep gives your tissues time to repair damaged cells and replace them, therefore, speeding up the time it takes to heal.
CBD relaxes your body and relieves chronic pain, making sure you get the sleep needed to accelerate healing. To treat chronic neck or back pain, you need between 2.
This can change depending on your body metabolism and weight. Consult your doctor to get the right dosage, or you can start off with a small dosage and move up so that you get the optimal dose for your condition.
This is why physicians are looking for an alternative way to manage chronic pain. CBD oil has been found to be the answer to this kind of pain and to this end, massive research has been undertaken to make sure the oil delivers the expected analgesic results. Some people have found that CBD oil has helped them get off traditional painkillers.
This agent attaches to specialized receptors found in your brain as well as the immune system. The major receptors that are involved in anti-inflammatory and pain relief are the CB1 found in the brain and CB2 present in the immune system. When you use CBD oil, the cannabinoids attach onto these receptors, therefore activating their analgesic and anti-inflammatory properties. All these actions happen in the brain and the central nervous system.
Additionally, the oil stimulates the body to release natural cannabinoids in your body, which in turn attach to the receptors, magnifying the effect. The anti-inflammatory nature of the oil helps to reduce the pain that comes with inflammatory conditions. CBD oil also influences the action of the endocannabinoid system in the body. This system is responsible for regulating pain, process of wakefulness and sleep and the immune system functions.
So, apart from enjoying pain relief, you also get to sleep better. In whichever way it works, scientists believe that once the cannabinoids attach to the receptors, they make the receptor to respond to pain signals differently, subsequently reducing pain and inflammation.
To enjoy the effects of the oil, you need to talk to your supplier regarding the right dosage and method of application. For muscular pain, use topical application for best results. For other pain, opt for an oral suspension or tincture for pain relief. Depression is a pathology that affects all aspects of human life, including health, social life and productivity. If you notice that you lack interest in activities that you previously used to love, or you have a feeling of sadness that you cannot seem to let go of, then you are most probably suffering from depression.
Depression is a general term for various specific conditions such as bipolar disorder, persistent depressive disorder postpartum depression, manic depressive disorder and a host of other related conditions.
Studies show that more than million people regardless of age suffer from this condition worldwide, reason why it became urgent that scientists find a lasting solution to the problem. This solution came in form of CBD oil. CBD oil has been found to have a great psychiatric potential, especially when it comes to treating depression. BD oil has been found to work better and faster than traditional antidepressants.
CBD oil works by triggering the endocannabinoid system, as well as accelerating the development and growth of nervous tissues with minimum side effects. Since it is a natural remedy, patients have the peace of mind that they cannot get with other medications. On top of this, CBD oil also helps to relieve anxiety, induce hunger, combat insomnia, enhance your mood as well as give you energy and focus for daily tasks.
Because one of the causes of depression is stress, using CBD oil has been found to stabilize the mood, helping to alleviate stress. For this task, you need to choose the perfect formulation for you among the available ones — tinctures, capsules, concentrates, tapes, sprays and topical applications. The cannabinoids, which are the active ingredients in the oil, attach to specific points in your brain cells to trigger actions of a hormone called serotonin.
Serotonin is a substance that improves your mood, alleviating stress levels. Serotonin also binds to specific receptors in the brain that trigger events that improve your mood. CBD also helps improve depressive symptoms by modifying the actions of endocanabinoids that are naturally produced in the body. It also amplifies the effects of serotonin by enhancing the activity of the special receptors that serotonin binds to.
The oil also has no potential for abuse or addiction, which is why it is ideal for treating depression. Since depression is a common occurrence for pregnant women, you are sure that using the oil in pregnancy cannot have any negative effect on the development of the fetus. However, you have to note that you get better results if you maintain a regular dose. Talk to your doctor to understand what dosage is perfect for you, but a start dose of 5mg to 10mg is ideal for individuals suffering from depression.
Maintain this dose until you achieve the desired results. If you are among the millions of people that suffer from insomnia, insufficient sleep or a related sleep disorder, you know how debilitating the condition can be. Like many people, you are always wondering if there is a way that you can sleep better. Question is, does CBD oil help you sleep? Yes, and research has proved that this oil can help you sleep much better than you do now.
It can also help treat sleep disorders. The most common cannabinoids on the market is THC, and the compound has been associated with the classic effects that are synonymous with cannabis. The effects include hunger, drowsiness and sleepiness. On the other hand, CBD oil comes with lower concentrations of THC, which means you can treat your insomnia without feeling high or getting addicted.
The need for CBD oil is that the active ingredients make you fall asleep faster. This means you get more time to sleep compared to using other methods to get to sleep. One of the benefits of using CBD oil is for treating pain-induced insomnia. Of notable mention is post-operative pain, which makes it hard for you to sleep.
However, with CBD oil, this becomes easier due to its anti-inflammatory and analgesic properties. So, CBD oil helps to soothe your body while assisting in recovery of the body from pain. Additionally, the antidepressant properties of CBD oil means that if you have insomnia due to fear or a racing mind, then CBD oil can calm you enough to help you fall asleep. Better yet, CBD oil has fewer risks as compares to other treatments used for insomnia. Additionally, overdose is non-existent.
The secret to better sleep is to use the right formulation, and administer it at the right time. For this, talk to your doctor or a consultant who understands the workings of the oil. Generally, start with a low dose and build on it depending on the results.
You also need to know when to administer it. In smaller doses, CBD oil stimulates alertness, which in turn reduces sleepiness that comes during daytime. This is vital for proper daytime performance and for the consistency of the all-important sleep-wake cycle. In April , she had an accident that required double bypass surgery. As a result of this, she ended up with chronic pain arising from a maligned sternum. Alice took painkillers continuously to relieve the pain, all in vain.
Two surgeries down the line and the doctors tell her that she has to undergo radiation. Some research showed that the radiation procedure would potentially lead to permanent damage to the nerves and lead to scarring. She decided to try CBD oil for treatment. Two weeks down the line and the cancer was subsiding, the pain was gone and the initial prognosis had changed from worse to good. She continued to use the CBD oil as recommended and as I speak, she is fit and full of life.
Over the years, evidence has been mounting that connects CBD and cancer relief. This is because CBD contains pro-apoptotic and anti-proliferative characteristics that reduce the growth of cancerous tissue. It interferes with cell adhesion, migration and invasion. So, how does CBD help in a cancerous situation?
One of the issues that crops up in a cancer patient is nausea. One of the ways that CBD helps in such situations is to treat nausea and subsequent vomiting. Cancer also damages nerves in patients, leading to chronic pain. Failure to handle anxiety disorders can impact relationships and work. These disorders impact millions of adults in the US aged 18 years or older. Drug store shelves are awash with anxiety related drugs ranging from tranquilizers to selective serotonin reuptake inhibitors. Well, not all drugs are effective, and the side effects are monstrous.
This is when CBD oil takes precedence. CBD delivers positive effects for a number of disorders including panic disorder, social phobia, obsessive compulsive disorder, moderate depression and post-traumatic stress disorder.
CBD works by helping the brain to transmit serotonin signals in the brain, which in turn reduces anxiety and boosts your mood. It does this by attaching receptors that control mood, sleep, stress, fear, irritability and cravings.
It also acts like a 5-HT1 receptor agonist, which plays a big role in serotonin pathways to reduce depression and anxiety. You can take CBD oil for anxiety in various ways.
The most common ways are capsules, tincture, sprays and vape. The mode you use will depend on how often you want to take the oil. Capsules are ideal for beginners who want to understand their CBD thresholds. Weight loss is one of the major areas of health that is tough to handle. Many people find it hard to lose that nagging body fat. Research has shown benefits of CBD for prevention and treatment of obesity.
So, what does CBD oil do for your weight? First, it has been found to stimulate proteins and genes that increase the breakdown of fat. Over time, this action leads to loss of excess weight. Your body depends on mitochondria to burn calories. CBD oil enhances the number and accelerates the activity of mitochondria. These mitochondria gives your body extra ability to burn calories.
One of the ways that your body accumulates fat is by generating fat cells through a process called lipogenesis. CBD oil reduces the rate at which these cells are generated, leading to a reduction in fat accumulation. One way to get CBD into the body fast is via use of the spray. Oral absorption is 90 percent effective; making sure your body utilizes all the nutrients in the oil.
The active ingredients in the oil go directly to the blood stream and into the fat cells in a matter of minutes. There has been debate over the years regarding the role of CBD oil in treating various neurological conditions as well as epilepsy.
Studies have shown a reduction in seizures by up to 40 percent in children and adults alike. Seizures are as a result of brains that are over-excited and fire abnormally, in most cases due to an unknown cause. Most patients suffering from epilepsy suffer from what is referred to as treatment-resistant epilepsy. CBD has proven to be a solution to this category of patients. The use of CBD oil has registered a reduction in the severity of seizures with both behavioral and physical improvements in both adults and children.
The results were documented with over the more than 25 CBD oil preparations available for use. Studies have identified certain compounds in CBD that might be helpful in treating autism. One of the ways that CBD oil works is by improving some of the symptoms of autism, including panic disorders, anxiety, aggression, tantrums, generalized rage and property destruction. Other studies have showed that certain compounds in CBD helps treat behavioral issues in children suffering from autism.
One of the issues that come up with every treatment is dosage regulation. The results you achieve are all about the dosage you administer. Low doses are good; an optimal dose is the best. High doses can be detrimental to health.
This condition has no cure at all, with very little options for treating this limiting and painful condition. One of the alternatives that is creating a lot of buzz is the use of CBD for anti-inflammatory purposes and for pain relief. Studies have shown a high level of CB2 receptors in joints of patients suffering from arthritis. The use of CBD has shown reduction in inflammation in these joints by giving these CB2 receptors a pathway to dissipate.
Another theory utilizes the role of CBD in repairing damaged nerves. The nerves in joints are stripped off their coating, which is the reason why you feel a lot of pain. By using CBD topical on these joints, you are able to repair them and decrease the pain associated with the condition. CBD has been shown to have an effect on high blood pressure, something attributed to its analgesic and anti-inflammatory properties. The best way to administer CBD for this condition is via tinctures or capsules.
Once considered dangerous, CBD is now a popular method to beat addiction. Research has shown that CBD can help you beat a wide variety of addiction ranging from smoking, alcohol addiction to substance abuse. It does this in various ways. For one, CBD reduces substance-seeking behavior, which in turn helps prevent craving and relapse. One of the major reasons for relapse is neurodegeneration. CBD has been shown to treat neurodegeneration, helping prevent relapse especially in alcoholics.
The potential ability of CBD to reduce anxiety levels is also one of the ways that opioid-dependent individuals can get rid of this addiction. There is a wide variety of preparations available for you to choose from, each having its own advantages and downsides.
The first tip is that you need to work with a genuine supplier. This is because with the buzz surrounding this compound, most people are coming up with an excuse to make a quick buck.
Work with a reputable supplier. Secondly, start small and build on the dosage depending on the reactions you observe. Move step by step to be able to know your optimal dosage. Finally, make sure you consult with an expert or a medical profession before starting on a regimen. Always follow the instructions that come with the preparation so that you use the oil as directed. Remember, each condition requires a certain dosage and a particular route of administration.
The oil comes in a variety of products including lotions, capsules, tinctures, lotions and many more. This paradox can cause you more stress. Let us analyze the top ways to take this beneficial product, when it is recommended and how to use it the right way. This is the most common way to use CBD. The main reason for this is because it is among the pure CBD oil products available for your consumption. You can choose plain oil or go for a little flavor. This flavor makes it easier for you to consume the oil.
The tincture comes in various flavors such as vanilla, cinnamon and peppermint, with added sweeteners to make the CBD easier to ingest. You take the oil by dropping a few drops under or on your tongue.
The dosage ranges from — mg, which means that you do some research on the strength you need before you make the order. The strength you choose depends on the issue you wish to treat using the oil. The only downside of using tinctures is that you must be very careful when using it to avoid spilling the oil.
A few extra drops under the tongue might seem awkward, especially when you use the oil daily. Tinctures are easy to modify to suit your varied needs. This is because you can increase the number of drops using the precise dropper that accompanies the package. Tinctures are more effective when taken sublingually. Instead, place a few drops depending on the recommendation under the tongue or along your cheeks for maximum absorption.
You can as well put a few drops of the tincture in your drink to make it easier for you to take. These are standard capsules that you see in drug stores, but they hold a certain amount of powdered hemp oil. The powder contains a high concentration of CBD. Capsules represent the easiest ways to add CBD to your daily routine. Capsules are much easier to take than tinctures and concentrates. If you are on vitamins, it becomes much easier to add capsules to your daily regimen. The capsules are odorless and tasteless, and just like pills, they are packaged in such a way that you can easily carry them around anywhere you go.
Capsules give you between 10 — 25mg of CBD. Each capsule therefore delivers a specific concentration of CBD making it easier for you to monitor your daily dosage. This means you have to depend on the standard capsule size to increase the dosage. One way to handle this is to use other product types such as tinctures that you can have total control over. The good news is that you can combine two products to get the serving size you need.
For instance you can decide to add a few drops of tincture to get the optimum serving size. The package comes with a number of capsules to help you choose the right quantity for you.
CBD Oil: A Cure for Depression?
Dec 30, For people with anxiety, CBD oil is touted as an all-natural way to find relief. according to the Anxiety and Depression Association of America. Interested in trying CBD oil to help with sleep and/or anxiety? Depression and anxiety: Both depression and anxiety disorder have been linked to sleep. Jun 27, Cannabis oil can be added to nourishment or basically dropped straight under the tongue for sublingual CBD Oil for Anxiety and Depression.