A groundbreaking study has documented the superior properties of whole plant CBD-rich cannabis extract as compared to single-molecule CBD. The article. SINGLE COMPOUND VS. WHOLE PLANT CBD. A groundbreaking study has documented the superior therapeutic properties of whole plant. A groundbreaking study from Israel has documented the superior therapeutic properties of whole plant CBD-rich cannabis extract as compared.
plant Single compound vs. whole
This cultivar is named after the cannabidiol pioneer, Lawrence Ringo. Shortly thereafter, other scientists began testing isolated cannabinoids on lab animals; notably, Walter S. Cannabis made another leap forward in when Israeli scientist Dr.
Raphael Mechoulam identified the structure of deltatetrahydrocannabinol, or THC. This discovery earned him godfather status of modern cannabis. In February of , Dr. Mechoulam teamed up with South American researchers to publish a study regarding cannabis and epilepsy. This study is seen as one of the earliest double-blind studies of CBD on clinical subjects. Mechoulam and his team conducted included 16 people, many of whom were children, who all suffered from severe epilepsy.
The results were startling: Every subject who received CBD experienced improvement in their condition with little to no side effects.
This anticonvulsant study has since proven to be an integral milestone in the world of clinical marijuana research, but largely went unnoticed at the time. In , a group of scientists researched and studied the effects of CBD on anxiety and found that it has potent anxiolytic, or anti-anxiety, properties as well.
This groundbreaking moment paved the way for public support and lucrative research opportunities. Geoffrey Guy and Dr. Brian Whittle to found GW Pharmaceuticals, a company that would utilize clinical trials to unpack various cannabinoid formulations as potential therapies with the overriding focus of developing what would later be known as Sativex Nabiximols.
These mounting developments in the elicited a problem amongst cannabis cultivators across the US: Essentially, CBD had been selectively bred out of existence across the country. Years passed, and more studies rolled out with medically beneficial findings regarding cannabis until when Steep Hill Laboratory in Oakland, California, tested cannabis samples provided by Harborside Health Center to discover that a handful of cultivars contained more CBD than THC.
This discovery kicked other labs into gear. They wanted to study medical cannabis to understand and potentially calibrate their cannabinoid ratios. Soon thereafter, laboratories uncovered CBD-dominant strains boasting Cannabidiol is as versatile as THC — perhaps even more so. Through science and determination, CBD has worked its way into an entire host of products. Combusting or vaporizing flower allows users to almost immediately feel the therapeutic effects of CBD.
CBD isolate is cannabidiol in its purest form: CBD can also be purchased in concentrate form, including raw CBD oil, cartridges, vape pens, syringes and more. Research and opportunity have driven chefs and chemists to infuse CBD into all sorts of readily usable products, such as edibles to elixirs, sublingual sprays, capsules and even topicals. Much like concentrates, each infusion sports specific combinations or isolations of CBD, THC, and other cannabinoids, allowing users to pick and choose products that suit their exact needs.
CBD topicals, for example, are incredibly effective when applied to surface-level problems like bruises, joint aches, and headaches, and have been scientifically proven to successfully combat skin-based issues including pruritus with far broader implications. According to the federal government, Schedule I drugs are substances or chemicals with no currently accepted medical use and a high potential for abuse.
To further confuse the American citizenry, some states permit patients the use of CBD, but require that they travel to another state to purchase it.
The mosaic of laws that govern CBD legality across the globe varies just as much as the legislation across the US. This paper has citations. From This Paper Figures, tables, and topics from this paper. Citations Publications citing this paper.
Showing of 85 extracted citations. Falade , Favour Komoni , Roseangela I. Wayanin and guaijaverin, two active metabolites found in a Psidium acutangulum Mart.
A phylogenetic road map to antimalarial Artemisia species. Hepatoprotective properties of fennel seeds extract. Citation Statistics Citations 0 20 40 '12 '14 '16 ' Semantic Scholar estimates that this publication has citations based on the available data. The philosophy may be understood best as isolating a particular effect. However, when we do this, we may be a little too smart for our own good.
At the end of the day, macro research can demonstrate this failing. When we run comparative tests we find that it turns out the orange is actually better than the vitamin C pill. When it comes to the therapeutic use of cannabis, we can see this perhaps more than anywhere else.
It should be obvious that using pieces of the cannabis plant lean far in the direction of eating the orange and far away from eating the vitamin C pill.
This is the field of whole plant extracts.
Project CBD Sunday: Single Compound vs. Whole Plant CBD
In traditional medicine whole plants or mixtures of plants are used rather than isolated compounds. There is evidence that crude plant extracts. Single Compounds Vs Whole Plants of what is important about the difference between a whole plant extract and a single compound drug. PDF | Background In traditional medicine whole plants or mixtures of plants are used rather than isolated compounds. There is evidence that.